Evolutionary development and co-phylogeny of primate-associated bifidobacteria

Lugli, Gabriele Andrea; Alessandri, Giulia; Milani, Christian; Mancabelli, Leonardo; Ruíz García, Lorena; Fontana, Federico; Borragán, S.; González, Andrea; Turroni, Francesca; Ossiprandi, María Cristina; Margolles Barros, Abelardo; Sinderen, Douwe van; Ventura, Marco; Science Foundation Ireland; Lugli, Gabriele Andrea [0000-0002-3024-0537]; Milani, Christian [0000-0002-5062-3164]; Mancabelli, Leonardo [0000-0002-1744-2214]; Turroni, Francesca [0000-0001-5363-0231]; Margolles Barros, Abelardo [0000-0003-2278-1816]; Ventura, Marco [0000-0002-4875-4560]

Evolutionary development and co-phylogeny of primate-associated bifidobacteria

2020

In recent years, bifidobacterial populations in the gut of various monkey species have been assessed in several ecological surveys, unveiling a diverse, yet unexplored ecosystem harbouring novel species. In the current study, we investigated the species distribution of bifidobacteria present in 23 different species of primates, including human samples, by means of 16S rRNA microbial profiling and internal transcribed spacer bifidobacterial profiling. Based on the observed bifidobacterial‐host co‐phylogeny, we found a statistically significant correlation between the Hominidae family and particular bifidobacterial species isolated from humans, indicating phylosymbiosis between these lineages. Furthermore, phylogenetic and glycobiome analyses, based on 40 bifidobacterial species isolated from primates, revealed that members of the Bifidobacterium tissieri phylogenetic group, which are typical gut inhabitants of members of the Cebidae family, descend from an ancient ancestor with respect to other bifidobacterial taxa isolated from primates.

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Joint Programming Initiative A healthy diet for a healthy life. Grant Number: 15/JP‐HDHL/3280. Science Foundation Ireland. Grant Numbers: SFI/12/RC/2273a, SFI/12/RC/2273b

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Peer reviewed

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