The haplotype-resolved T2T reference genome highlights structural variation underlying agronomic traits of melon
Li, Guoli | Tang, Lingli | He, Yuhua | Xu, Yongyang | Bendahmane, Abdelhafid | García-Mas, Jordi | Lin, Tao | Zhao, Guangwei | Chinese Academy of Agricultural Sciences | Earmarked Fund for China Agriculture Research System | Hainan Province | European Research Council | Henan Province
Melon (Cucumis melo L.) is an important vegetable crop that has an extensive history of cultivation. However, the genome of wild and semi-wild melon types that can be used for the analysis of agronomic traits is not yet available. Here we report a chromosome-level T2T genome assembly for 821 (C. melo ssp. agrestis var. acidulus), a semi-wild melon with two haplotypes of ~373 Mb and ~364 Mb, respectively. Comparative genome analysis discovered a significant number of structural variants (SVs) between melo (C. melo ssp. melo) and agrestis (C. melo ssp. agrestis) genomes, including a copy number variation located in the ToLCNDV resistance locus on chromosome 11. Genome-wide association studies detected a significant signal associated with climacteric ripening and identified one candidate gene CM_ac12g14720.1 (CmABA2), encoding a cytoplasmic short chain dehydrogenase/reductase, which controls the biosynthesis of abscisic acid. This study provides valuable genetic resources for future research on melon breeding.
Показать больше [+] Меньше [-]This work was supported by funding from the Agricultural Science and Technology Innovation Program (CAAS-ASTIP-2016-ZFRI-06), the China Agriculture Research System (CARS-25-2023-G6), the Key Research and Development Program of Hainan (ZDYF2021XDNY164), the European Research Council (ERC-NectarGland, 101095736), the 111 Project (B17043) and Henan Province Science and Technology Research Project (232102110185).
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