THE ANTI-PROTOZOAL EFFECTS OF PRAZIQUANTEL ON GIARDIASIS IN MICE
2005
Zainab H. Gany | Nadham K. Mahdi
The chemotherapeutic effects of anti-eestodes drug praziquantel on giardiasis in laboratory mice. Fourty mice were divided into 4 groups of 10 mice each. Group 1 was infected; group2 was infected and treated orally by giving praziquantel at a dose of 10 mg/kg body weight as a single dose; group 3 was infected and treated orally by giving metronidazole at a rate of 15-20 mg/kg body weight daily for 7' days; group 4 was uninfected. Cyst excretion rate was recorded for the infected groups of mice. The infected and praziquantel treated mice have recovered much more faster than infected mice and treated by metronidazole. There were no side effects reported. Praziquantel proved for the first time to be an ideal drug for the treatment of giardiasis
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