Sibling Resemblance in Physical Activity Levels: The Peruvian Sibling Study on Growth and Health
2023
Carla Santos | José Maia | Sara Pereira | Olga Vasconcelos | Rui Garganta | J. Timothy Lightfoot | Go Tani | Donald Hedeker | Peter T. Katzmarzyk | Alcibíades Bustamante
Physical activity is associated with a host of positive health outcomes and is shaped by both genetic and environmental factors. We aim to: (1) estimate sibling resemblance in two physical activity phenotypes [total number of steps∙:day&minus:1 and minutes for moderate steps per day (min∙:day&minus:1)]: and (2) investigate the joint associations of individual characteristics and shared natural environment with intra-pair sibling similarities in each phenotype. We sampled 247 biological siblings from 110 nuclear families, aged 6&ndash:17 years, from three Peruvian regions. Physical activity was measured using pedometers and body mass index was calculated. In general, non-significant variations in the intraclass correlation coefficients were found after adjustment for individual characteristics and geographical area for both phenotypes. Further, no significant differences were found between the three sib-ship types. Sister-sister pairs tended to take fewer steps than brother-brother (&beta: = &minus:2908.75 ±: 954.31). Older siblings tended to walk fewer steps (&beta: = &minus:81.26 ±: 19.83), whereas body mass index was not associated with physical activity. Siblings living at high-altitude and in the Amazon region had higher steps/day (&beta: = 2508.92 ±: 737.94: &beta: = 2213.11 ±: 776.63, respectively) compared with their peers living at sea-level. In general, we found no influence of sib-types, body mass index, and/or environment on the two physical activity phenotypes.
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