Attempts of these studies were made to investigate the nonspecific congenital focal accumulation of etcodermal glial cells in the brain of normal piglets. The brain samples were taken from 1-, 10-, 20-, 35-, 45- and 70-day-old piglets from a SPF-pig farm and three model pig farms. Occurrences of neuroglial cell foci(NCF) on the brain were observed with light microscope. Appearance degrees of the congenital NCF on 10 to 16 cross section slides per a piglets brain were tentatively designed on a scale from deg. + to +++ by NCF number: +, less than 20 of NCF number; , 21-40 of NCF number: +++ , more than 41 of NCF number. NCF in the brain were obseved mainly on the cerebrum. Regions of higher frequencies on the cerebrum were ordered as subependymal layers of the lateral ventricles, peripheral regions of lateral ventricles in the white matter and some neuron layers under the molecular layer of the gray matter. But NCF were not observed in the cerebellum, pons, medulla oblongata and spinal cords. On the subependymal layers of the lateral ventricles, NCF were observed in 100% of 27 piglets, and appearance degree of was observed in 10 piglets (37.0%), ++ in 10 piglets (37.0%) and + in 7 piglets (26.0%) of 27 piglets, respectively. On the white matter of the cerebrum, NCF were observed in 25 piglets (92.6%) of 27 piglets, and appearance degree of +++ was observed in 3 piglets (11.1%), in 13 piglets(48.2%), + in 9 piglets (33.3%) and- in 2 piglets (7.4%) of 27 piglets, respectively. On the gray matter of the cerebum, NCF were observed in 21 piglets (77.8%) of 27 piglets, and appearance degree of +++ was not observed, appearance degree of ++ was obseved in 6 piglets (22.2 %), + in 15 piglets (55.6%) and - in 6 piglets (22.2%) of 27 piglets, respectively. NCF tended to be converged appearance on some regions and tended to be decreased markedly from 35th day after birth, and the shapes of NCF were global or oval forms crowded by analogous shaped and stained cells in the empty spaces of the brain substrate or on one side of the blood vessels

For the laboratory diagnosis of Sarcocystis infections especially in domesticated food animals, several antificial digestion techniques were applied for the musculature specimens and several staining techniques wes applied for the bradyzoites of Sarcocystis species isolated. The digestion technique using trypsin (0.5%) and sodium chloride (0.85%) mixed solution was regarded as the most valuable for the detection of asexual stages of Sarcocystis in bovine musculature specimens. Optimal time for digestion was approximately one to four hours. The trypsin digestion technique with Giemsa's stain could be helpful for the detection of Sarcocystis proliferative forms and for the observation of the nucleus of the parasite. A systematic detection was also performed in an autopsy for a bovine carcass naturally infected with Sarcocystis species, and the asexual stages such as metrocytes and bradyzoites were observed in the specific organs, respectively

Normal swine brains at 1 to 70 days after birth were used to investigate the presence and morphology of the subependymal layer (SL) in the ventricle walls. The brain samples were taken from 27 pigs of 4 swine breeds. SLs were observed on the walls of the lateral ventricle (LV) but none were observed on the walls of the 3th and 4th ventricles. SLs of the LV walls were composed of mainly 3-to 10-cell layers in thickness. The thinnest region of SLs was composed of only 1-to 2-cell thick on the dorsal and ventral walls, and the thickest region was composed of 250-to 300-cell thick on extension region of the SLs into the angle between the corpus callosum and caudate nucleus. SLs were extensively thick in young age but gradually decreased in size and cell number with age after 20-day age. SL layers were composed of mainly oligodendrocytes, astrocytes and immature cells of them. Morphological differences of SL in different breeds of pigs were not observed.

Observations were made on the blood picture of 50 multiparous and 98 infertile cows. Mean values of RBC, Hb, PVC, MCV, MCH, MCHC and platelets for normal multiparous cows were 6.87+-0.84X10** (6)/mm** (3), 10.3+-1.3g/100ml, 31.4+-3.7ml/100ml, 46.1+-6.9u** (3), 15.3+-2.6pg, 34+-2.7%, and 372.7+-304.7X10** (3)/mm** (3) respectively. Mean values of RBC, Hb, PVC, MCV, MCH, MCHC and platelets for infertile cows were 7.00+-0.98X10** (6)/mm** (3), 10.6+-1.2g/100ml, 32.1+-3.6ml/100ml, 45.8+-6.7u** (3), 15.3+-1.8pg, 33.9+-3.3%, and 382.7+-157.5X10** (3)/mm** (3), respectively. Mean values of WBC count for normal multiparous and infertile cows were 7.92+-1.72 and 9.04+-2.87X10** (3)/mm** (3) respectively. In the differential leukocytes count, mean values of neutrophils, lymphocytes, monocytes, eosinophils and basophils for normal multiparous cows were 29.7+-7.9%, 56.8+-7.6%, 2.9+-1.9%, 9.9+-5.3% and 0.3+-0.7%, respectively, and mean values of neutrophils, lymphocytes, monocytes, eosinophils and basophils for infertile cows were 31.9+-7.8%, 57.5+-7.9%, 2.6+-1.9%, 7.5+-4.8%, and 0.4+-0.2%, respectively

A preliminary survey of Sarcocystis species in the slaughtered cattle in Seoul was undertaken during October through December 1987, using digestion diagnostic technique for the heart muscle specimens digested in 0.5 % trypsin solution. Results indicated that 41.5 % of 159 bovine hearts were infected with Sarcocystis proliferative forms. High frequencies in the exotic dairy cattle (42.2%) and the Korean native cattle (41.7%) were noticed in comparison with low frequency in the cross breed (25.0%). No differences were indicated between the sexes of the host animals, although an age difference was noticed as 48.9 % in cattle older than four years in comparison with 39.0 % and 37.1 % in younger than two years and in two to four years, respectively

To determine the prevalence and the morphological identification of two Eimeria species in fecal examinations, a total of 1092 fecal specimens collected during the period of March to December in 1987 was tested by means of flotation technique. The prevalence of two species was revealed as 1.83% and 0.92% in E. bukidnonensis and E. wyomingensis, respectively. The oocysts of E. bukidnonensis measured in range of 41.3 micro m to 49.4 micro m (mean 45.5+-1.7) x 28.8 micro m to 35.3 micro m (mean 32.2 +-1.2), and E. wyomingensis 36.9 micro m to 44.5 micro m (mean 39.8+-1.7) x 26.5 micro m to 29.9 micro m (mean 28.2+-0.9). The oocysts of E. bukidnonensis appeared darker and more robust than those of E. wyomingensis. The striations in the oocyst wall of E. bukidnonensis were more peculiar than in E. wyomingensis. Among the morphological characteristics, the widths could be reliably taken as a differential point of view for two Eimeria species

Xylazine hydrochloride is a widely used analgesic, sedative and muscle relaxant in veterinary clinic. Yohimbine hydrochloride and 4-aminopyridine are known as antagonists of xylazine hydrochloride. This paper investigated whether or not there exists an antagonism of yohimbine hydrochloride and 4-aminopyridine to xylazine hydrochloride. After xylazine hydrochloride administration, the gizzard motility in chicken was instantly inhibited in relaxation state, and this state was prolonged as the dose was increased. After yohimbine hydrochloride administration, the gizzard motility in chicken showed increase of contractile frequency. After 4-aminopyridine administration, the gizzard motility in chicken was gradually recovered next to decrease of contractile amplitude and frequency. After the combination of yohimbine hydrochloride and 4-aminopyridine administration, the gizzard motility in chicken showed increase of amplitude and radical increase of frequency. After xylazine hydrochloride administration, the relaxation time was shortened by yohimbine hydrochloride, 4-aminopyridine and the combination of yohimbine hydrochloride and 4-aminopyridine. In conclusion, the gizzard motility in chicken was inhibited by xylazine hydrochloride, and this effect was antagonized by combination of yohimbine hydrochloride and 4-aminopyridine

The present study was carried out to investigate the estrous behavior and vaginal smear after induction of estus with exogenous hormones in the premature, metestrous and anestrous bitches. In a total of 21 bitches(Mixed breed: 16, Jindo breed: 5), from 10 months to 5 years of age and weighing 8 to 15 kg the change of vaginal smear and the estrous behavior before and after induction of estrus was studied. In the treatment A(They were given the PGF2alpha, estrone, estradiol-17beta, PMSG and HCG) proestrus commenced in 10.16+-1.44(Mean+-SEM) days after treatment. The mean duration of proestrus and estrus was 7.50+-1.44 and 13.50+-3.44 days, respectively. In the treatment B(They were given the PMSG and HCG) proestrus commenced in 5.53+-0.59 days after treatment. The mean duration of proestrus and estrus was 6.60+-0.71 and 14.60+-1.14 days, respectively. All of the 6 bitches in the treatment A showed vulval swelling and vaginal discharge. 14 of the 15 bitches in the treatment B showed vulval swelling and vaginal discharge. However, all of the treatment A and B showed male acceptance. The main change of vaginal smear in proestrus and estrus after induction of estrus was an increase in the proportion of anuclear and superficial cells associated with a decrease in small intermediate and parabasal cells. By the estrous behavior and vaginal smear the estrus was induced in all the premature, metestrous and anestrous bitches

Attempts were made to determine the clinical features and the causative organism of ringworm occurring in a cat in Chinju city, Korea. Alopecia and greyish white crusty lesions were obseved around the eye, nose and posterior limb while irregular, partial loss of hairs and white scales were in the ear, neck and abdomen lesions. Direct microscopic and cultural examination were carried out for the hairs and crusts taken from the skin lesions, and the causative organism was identified as M. canis

To examine the selectivity of diltiazem, used in the cardiovascular diseases, on alpha-1 and alpha-2 adrenoceptor-induced pressor responses, effect of diltiazem on alpha-adrenoceptor agonist-induced pressor responses were investigated in urethane-anesthetized rabbits and spinal rabbits. Intravenous diltiazem(10,30,100,300,1000 micro g/kg) produced dose-dependent depressor response in rabbits. Pressor responses to intravenous norepinephrine(10 micro g/kg) and phenylephrine (30 micro g/kg) were inhibited by pretreatment with intravenous diltiazem in rabbits and no difference was noted between the degree of both inhibitions of the pressor response by diltiazem. Pressor responses to intravenous norepinephrine (3 micro g/kg), phenylephrine (20 micro g/kg) and clonidine (300 micro g/kg) were inhibited by pretreatment with intravenous diltiazem in spinal rabbits. No difference was noted between the inhibition of norepinephrine-induced pressor response and that of phenylephrine-induced pressor response by diltiazem. The inhibition of clonidine-induced pressor response by diltiazem was slightly more prominent than that of norepinephrine-or phenylephrine-induced pressor response. These results suggest that diltiazem significantly inhibits both pressor responses mediated by alpha-1 and alpha-2 adrenoceptors