This study was conducted to survey of Ehrlichia (E.) canis and Borrelia (B.) burgdorferi antibodies among clinically healthy German shepherd dogs (116 females and 120 males) using a ELISA kit (SNAP 3Dx; IDEXX Laboratories, USA) in Korea. Whole blood samples are collected from the 236 dogs and are tested to detect E. canis and B. burgdorferi antibodies by using ELISA kit (SNAP 3Dx; IDEXX Laboratories, USA). Confidence interval comparisions revealed that dogs of 4-6 years have higher prevalence with a seropositive result (CI = 0.17 - 0.45) in E. canis than the other age groups but there are no differences among age groups in B. burgdorferi.

Olive flounder, Paralichthys olivaceus is one of the most important cultured fish in Korea, its farming has been negatively impacted by viral, bacterial and parasitic diseases. Streptococcal infection was considered as a serious problem because of significant economic losses in olive flounder farm industry. The development and evaluation of vaccine for protection against infection by this agent were required. We evaluated the safety and efficacy of β-hemolytic Streptococcus (S.) iniae vaccine on olive flounder.

Neoheterobothrium hirame (N. hirame) is a large blood-feed gill-worm infecting the highly prized olive flounder. The present study was reported the occurrence and elimination of Neoheterobothrium infection from young cultured oliver founder in the western coast of Korea. Flounder (weight 18-25 g, length 10-15 cm) were obtained from a cultured farm at Taean of Korea at May 2006. A lot of flounder died with serious anemia. We isolated N. hirame from the buccal cavity wall of dead flounder. Adult parasites were 5-15 mm in total length, with 4 pairs of clamps on the pedunculated haptor and isthmus region embedded in host tissue, while immature and sub-adults were identified the attachment to the gill filaments, rakers and arches with the clamps.

A-7-year-old, intact female Korean Jindo dog was referred due to ataxia and pain on palpation of the thorax. Radiograph, echocardiography and computed tomogram revealed a mass on the heart base region and osteolytic change of fifth thoracic (T5) vertebra. At necropsy, a firm, encapsulated and round mass was seen arising from the heart base region surrounding the ascending aorta and pulmonary artery. Histopathologically, nests of cuboidal and polyhedral cells having abundantly granular and eosinophilic cytoplasm with round to oval nucleus were separated by fibrous septa.

An intact male, 3-month-old, Great Pyrenees mountain dog, weighing 7.3 kg with a history of severe hematuria during 2 months was referred. Hematology showed mild leukocytosis. There were no remarkable findings in abdominal radiographs due to ingesta and gas in the gastrointestinal tracts. Ultrasonographs showed bilateral hydronephrosis, bilateral dilated and tortuous ureters, and hyperechoic sludges in the urinary bladder (UB). And a dilated cavity was identified cranial to the UB. Excretory urography and cystography were performed to examine the cause of hydronephrosis and an abnormal cavity cranial to the UB.

The cases of feline panleukopenia virus (FPLV) infection were diagnosed in three imported cats. All cats died within one week after mild emaciation, depression and anorexia. One cat showed yellowish watery diarrhea. At necropsy, all cats had segmental hemorrhage on the serosa and mucosa of the small intestine. Histopathologically, severe diffuse necro-hemorrhagic enteritis was observed in small intestine especially in jejunum and ileum. The crypts of Lieberkuhn were dilated and contained necrotic epithelia. Severely damaged epithelia of crypts were transformed into bizarre shapes.

The approval of use of certain food-grade phosphates as food additives in a wide variety of meat products greatly stimulated research on the applications of phosphates in foods. Although phosphates have never been classified as antimicrobial agents, a number of investigators have reported that phosphates have antimicrobial activities. Phytic acid is a natural plant inositol hexaphosphate constituting 1-5% of most cereals, nuts, legumes, oil seeds, pollen, and spores. In this study, we investigated antibacterial activities of sodium phytate (SPT), sodium pyrophosphate (SPP), sodium tripolyphosphate (STPP) on Salmonella typhimurium in tryptic soy broth and in row meat media including chicken, pork and beef.

A 6-year-old female Maltese dog (body weight 2.0 kg) was referred to the Veterinary Teaching Hospital. Kangwon National University with primary complaints including exercise intolerance and heart murmur. Based on clinical and diagnostic findings including grade V/VI left basal continuous murmur, bounding femoral pulsation, left ventricular enlargement pattern in electrocardiogram, cardiomegaly with aortic bulging on the thoracic radiography, and shunt flow between aorta and pulmonary artery on the echocardiography, the dog was diagnosed as the left-to-right patent ductus arteriosus.

A 2-year-old spayed female ferret with the clinical signs of diarrhea and anorexia for about 8 days was presented to Hansung animal hospital. The diarrhea was black and paste form. Three palpable abdominal masses were detected in physical examination. By cytologic examination using fine need aspiration, the patient was tentatively diagnosed as lymphoma. Chemotherapy was started with prednisone, vincristine and cyclophosphamide. However, the client requested stopping the therapy at day 18 and the ferret was euthanized.

The efficacy of oil extract of the seeds of Loranthus europeus on wound healing was investigated. After the preparation of the oil extract, the oil ointment of L. europeus was prepared. A preliminary biochemical analysis were carried out to find out the chemical contents of L. europeus oil extract. The study involved 18 male rabbits, they were divided equally and randomly into 3 groups depending on post wounding biopsy: p(3'd,7Ih and l4‘hday post wounding). Two full thickness cut wounds were done on the both sides of shoulder regions( the left wound as control and the left as treated wound) of each group of animals. The treated and control wounds were treated continuously with (0.5mg) oil ointment and Vaseline base respectively, for 14”‘ day twice a day. All wounds were evaluate macroscopically which included "measurement of contraction rate, daily wound contraction, hyperemia, exudation and scab formation." and microscopically for "neutrophil, macrophage infiltration, re-epithelization, fibroblast proliferation with collagen production and new blood capillary formation". A Both macroscopic and microscopic results showed the efficacy of L europeus seeds in promoting the healing process significantly as compared with control wounds (P