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Effect of contact time on variance of ground reaction forces during force platform gait analysis of a heterogeneous sample of clinically normal dogs Полный текст
2018
Hoffman, Christopher L. | Volstad, Nicola J. | Hans, Eric C. | Nemke, Brett W. | Muir, Peter
OBJECTIVE To develop contact time (ConT) and withers height-normalized relative ConT (ConT*) for force platform gait analysis of dogs. ANIMALS 29 healthy client-owned dogs. PROCEDURES Height at the most dorsal aspect of the shoulders (withers) was measured with a framing square. Dogs were trotted across a force platform at their preferred velocity with controlled acceleration (± 0.5 m/s2). Ranges of ConT and ConT* centered on the population mean ConT were created. Variance effects on ground reaction forces (GRFs) for 4 thoracic limb and 4 pelvic limb ConT and associated ConT* ranges were examined. Efficiency of trial capture and effects of velocity ranges on GRF variance were determined. RESULTS Individual dogs had the greatest effect on GRF variance for thoracic and pelvic limbs. Narrow ConT and ConT* ranges had few significant effects on GRFs but were inefficient at capturing trials. The ConT ranges of 0.22 to 0.29 seconds and 0.19 to 0.25 seconds for thoracic and pelvic limbs, respectively, provided the most efficient rates of trial capture with the fewest significant effects on GRFs. Compared with ConT and ConT* ranges, relative velocity ranges had higher efficiency and smaller GRF variance effects. CONCLUSIONS AND CLINICAL RELEVANCE Dogs of various morphologies have differing limb velocities. Use of ConT as a surrogate for limb velocity may improve GRF data quality. We identified ConT and ConT* ranges associated with low GRF variance. However, relative velocity ranges captured data more efficiently. Efficient capture of data may help avoid worsening of lameness during gait analysis of dogs.
Показать больше [+] Меньше [-]Cardiac weights and weight ratios as indicators of cardiac lesions in pigs: A study of pig hearts from an Ontario abattoir Полный текст
2018
Zurbrigg, K. | Van Dreumel, T. | Rothschild, M. F. | Alves, D. | Friendship, R. | O'Sullivan, T. L.
Clinically healthy pigs used in research are assumed to have normal cardiac structure and function. Subclinical cardiac abnormalities may adversely affect the responses being measured in these experiments. The gross and histologic lesions observed in hearts collected from a Canadian abattoir between 2012 and 2015 indicated an unexpectedly high prevalence of cardiac abnormalities: 75% (297/396) of the hearts examined had such lesions. The ratios of total heart weight to body weight and of right ventricle weight to body weight were significantly greater for the hearts with lesions than for the hearts with no lesions, which suggests that cardiac remodeling, particularly hypertrophy, had occurred. The large percentage of hearts with cardiac remodeling from asymptomatic market pigs demonstrates an increased probability that subclinical cardiac abnormalities may exist in research pigs, especially those accessed through commercial channels. Researchers should be aware of this likelihood if subclinical cardiac abnormalities could adversely affect their experimental findings.
Показать больше [+] Меньше [-]Effect of the addition of epinephrine to a lidocaine solution on the efficacy and duration of palmar digital nerve blocks in horses with naturally occurring forefoot lameness Полный текст
2018
Alvarez, Ana Velloso | Schumacher, John | DeGraves, Fred J.
OBJECTIVE To determine whether addition of epinephrine to a lidocaine solution would prolong and potentiate the efficacy of a palmar digital nerve block (PDNB) in horses. ANIMALS 6 adult horses with naturally occurring forefoot lameness. PROCEDURES Initially, a PDNB with a 2% lidocaine solution was performed on the affected foot of each horse. Three days later, the PDNB was repeated with a 1% lidocaine solution or a 1% lidocaine solution containing epinephrine (dilution, 1:200,000). After another 3-day washout period, the PDNB was repeated with the treatment opposite that administered for the second PDNB. Gait was analyzed with a computerized lameness analysis system and heart rate and extent of skin sensation between the heel bulbs of the blocked foot were evaluated at predetermined times for 2 hours after each PDNB. RESULTS Efficacy and duration of the PDNB did not differ significantly between the 2% and 1% lidocaine treatments. The addition of epinephrine to the 1% lidocaine solution improved the efficacy and prolonged the duration of the PDNB. It also resulted in a positive correlation between skin desensitization and amelioration of lameness. Median heart rate remained unchanged throughout the observation period for all 3 treatments. No adverse effects associated with the PDNBs were observed. CONCLUSIONS AND CLINICAL RELEVANCE Addition of epinephrine (dilution, 1:200,000) to a 1% lidocaine solution improved the efficacy and prolonged the duration of a PDNB in horses with naturally occurring lameness and might be clinically useful for lameness evaluations and standing surgery of the forefoot of horses.
Показать больше [+] Меньше [-]Effects of dexmedetomidine combined with commonly administered opioids on clinical variables in dogs Полный текст
2018
Nishimura, Lilian T. | Auckburally, Adam | Santilli, Juliana | Vieira, Beatriz H. B. | Garcia, Debora O. | Honsho, Cristiane S. | Mattos-Junior, Ewaldo de
OBJECTIVE To evaluate cardiopulmonary, sedative, and antinociceptive effects of dexmedetomidine combined with commonly administered opioids in dogs. ANIMALS 8 healthy Beagles. PROCEDURES Dogs were sedated by IM administration of each of 7 treatments. Treatments comprised dexmedetomidine (0.01 mg/kg; Dex) and the same dose of dexmedetomidine plus butorphanol (0.15 mg/kg; Dex-But), meperidine (5 mg/kg; Dex-Mep), methadone (0.5 mg/kg; Dex-Meth), morphine (0.5 mg/kg; Dex-Mor), nalbuphine (0.5 mg/kg; Dex-Nal), or tramadol (5 mg/kg; Dex-Tram). Cardiorespiratory and arterial blood gas variables and sedative and antinociceptive scores were measured before drug injection (time 0; baseline) and at 15-minute intervals for 120 minutes. RESULTS Heart rate was reduced at all time points after injection of Dex-But, Dex-Mep, Dex-Meth, and Dex-Mor treatments. There was a significant reduction of mean arterial blood pressure for Dex-But, Dex-Mep, and Dex-Mor treatments at all time points, compared with baseline. There was a significant decrease in respiratory rate, compared with the baseline value, for Dex, Dex-But, Dex-Meth, and Dex-Tram treatments from 15 to 120 minutes. A significant decrease in arterial blood pH was detected from baseline to 120 minutes for all treatments, with differences among Dex, Dex-Mep, and Dex-Mor. Reduction in Pao2 was greater for the Dex-Mep treatment than for the other treatments. The highest sedation scores were detected for Dex-Mep and Dex-Meth treatments. Antinociceptive effects were superior for Dex-But, Dex-Meth, Dex-Mor, and Dex-Nal treatments. CONCLUSIONS AND CLINICAL RELEVANCE Drug combinations caused similar cardiorespiratory changes, with greater sedative effects for Dex-Mep and Dex-Meth and superior antinociceptive effects for Dex-But, Dex-Meth, Dex-Mor, and Dex-Nal.
Показать больше [+] Меньше [-]Comparison of three computed tomographic angiography protocols to assess diameters of major arteries in African grey parrots (Psittacus erithacus) Полный текст
2018
Yu, Pin Huan | Lee, Yen Lin | Chen, Chia Li | Chi, Chau-Hwa
OBJECTIVE To evaluate 3 contrast medium infusion (CMI) protocols for CT angiography (CTA) and measurement of major artery diameters in African grey parrots (Psittacus erithacus). ANIMALS 9 African grey parrots with no detectable cardiovascular disease. PROCEDURES Each bird was anesthetized and underwent placement of an IV catheter in the left basilic vein and 16-slice CTA scanning (started at peak aortic enhancement) with each of 3 CMI protocols at ≥ 1-month intervals. Protocol 1 involved catheter flushing with saline (0.9% NaCl) solution and IV infusion of iopamidol (2 mL) followed by saline solution (0.2 mL; total infused volume, 5 mL). Protocol 2 involved IV infusion of iopamidol (2 mL) followed by saline solution (0.4 mL; total infused volume, 2.4 mL). Protocol 3 involved catheter flushing with saline solution and IV administration of iopamidol (2 mL; total infused volume, 4.8 mL). The diameters of 6 major arteries were measured by 2 observers, and intra- and interobserver agreement, time-enhancement variables, and patient factors affecting contrast medium enhancement were assessed. RESULTS Among the 3 CMI protocols, CTA-derived arterial diameters differed significantly. Measurements obtained with protocol 2 were significantly larger than those obtained with the other protocols. Uniformity of the time-enhancement variables differed among CMI protocols. Patient factors had nonsignificant effects on contrast medium enhancement. CONCLUSIONS AND CLINICAL RELEVANCE Of the CMI protocols assessed, a 2-phase CMI protocol with a post-CMI saline solution flush was the most reliable for CTA-derived measurements of the major thoracic and abdominal arteries in African grey parrots. However, further technique modification is needed.
Показать больше [+] Меньше [-]Study of Knowledge, Attitude and Action of Buffalo Breeders in the Villages Around Nagan Raya Power Plant on the Impact of Fly Ash Exposure Полный текст
2018
Susanti, Ira | Rinidar, Rinidar | Sugito, Sugito
One of the biggest contributors of air pollution is the production of coal fly ash from power plant industry. Fly ash has an immediate impact on human and animal health around the power plant. Many buffaloes in Nagan Raya usually grazing near the 110-megawatt steam power plant that using low rank coal. This action raises concerns about buffalos health due to exposure to fly ash. This study aimed to examine the relationship of knowledge, attitude and action of buffalo breeders to the impact of fly ash exposure on the buffaloes. This research used analytical survey with cross sectional design. This study was conducted in February 2018 with 30 respondents from four villages around Nagan Raya Power Plant to evaluate their knowledge, attitudes and actions by using questionnaires. The data were analyzed statistically with Chi Square Test with SPSS for Windows version 17.0. The results showed that there was no significant correlation between the knowledge of buffalo breeders and the impact of fly ash exposure (P 0.05), while the attitude and actions of buffalo breeders had a significant correlation with the impact of fly ash exposure (P 0.05). These results concluded that the buffalo breeders in the villages around the power plant did not realize the impact of fly ash arising from coal of power plant. It is expected that the associated institution would conduct a counseling about the impact of fly ash exposure as well as good management of buffaloes.
Показать больше [+] Меньше [-]Infectious Diseases of Six Non-Domesticated Neo-Tropical Animals In Trinidad and Tobago Полный текст
2018
Lall, Kavita Ranjeeta | Jones, Kegan Romelle | Garcia, Gary Wayne
This review serves to shed light on some common infectious diseases: their names, prevalence, site of infection and diagnostic tools for identificationof six (6) neo-tropical animals that are found in Trinidad and Tobago with the potential for domestication. These are theagouti(Dasyprocta leporina/ D. agouti), lappe/paca (Cuniculus paca/ Agouti paca), capybara (Hydrochoerus hydrochaeris), manicou/opossum (Didelphis marsupialis insularis), collared peccary (Tayassu tajacu/ Peccari tajucu) and red brocket deer (Mazama americana).There is over Ninety (90) references were used, with the earliest being 1951 and the most recent being in 2017.Where literature was lacking, information from other species within the same genus was incorporated and identified clearly. It was interesting to note that the majority of animals, despite being infected with pathogenic organisms were clinically healthy. In animals that showed clinical signs of disease there was a large quantity of pathogens present. This manuscript sheds some light on the pathogens that may use these animals as natural reservoirs. This review paper also includes many of the earliest identification of these pathogens in Neo-tropical animals in specific geographic regions.
Показать больше [+] Меньше [-]Eurytrematosis: a Review of the Pancreatic Fluke Полный текст
2018
Balqis, Ummu
Eurytrematosis is a common zoonotic disease has emerged as a major species causing veterinary diseaseand public health problem. This review examines recent advances in Eurytrema species, the life cycle, intermediatehosts required for completing the life cycle, and geographical distribution of Eurytrema species in the world, as wellas several factors considered suitable to occur.
Показать больше [+] Меньше [-]The Effect Of Cellulase Content On Phytoestrogens Formation (Genistein) Materials On Fermented Soybean Waste Aspergillus niger Полный текст
2018
Sutari, Vara Tassa | Nurliana, Nurliana | Sugito, Sugito | Darmawi, Darmawi | Rinidar, Rinidar
The activity of the cellulase enzyme and the content of phytoestrogen (genistein) forming is determined during the fermentation of soybean waste with Aspergullus niger. The analysis is performed at fermentation incubation time of 0, 48, 96, 144 and 192 hours and treatment with addition of micro nutrient (V2) and without micro nutrient (V1). Data analysis on cellulase enzyme activity on phytoestrogen forming material is performed using T test. The average of cellulase content of fermented soybean waste increases from 0.032-0.139 IU / ml (V1) and 0.061-0.158 IU / ml (V2) after 48 hours into 0.238 IU / ml (V1) and 0.245 IU / ml (V2) after 192 hours The average of genestein levels in the fermented soybean waste increases as well from 0.101 - 0.573 mg / g (V1) and 0.114 - 0.587 mg / g (V2) after 48 hours and increase into 0.722 mg / g (V1) and 0.699 mg / g (V2) after 192 hours. Statistical analysis indicates that the treatment of V1 and V2 has an effect on the increase of cellulase enzyme content and genistein level (P 0.05). The correlation between enzyme activity of cellulase and genistein on soybean waste fermented with Aspergillus niger is significant (R2 = 0,949). The relationship between the enzyme performance and its formation material is running synergistic, cellulase enzyme activity and genistein level experience significant increase during the fermentation process.
Показать больше [+] Меньше [-]The Relationship between Farmer Characteristic and Knowledge towards the Successfulness of Cattle Artificial Insemination (AI) in Aceh Besar District Полный текст
2018
Kardin, Julia | Dasrul, Dasrul | Sugito, Sugito | Nurliana, Nurliana | Helmi, Teuku Zahrial
The purpose of this research was to identify the relationship of characteristic and knowledge of farmers to the successful of artificial insemination (AI) in Aceh Besar Districts. The number of respondents is 93 people from twenty three districts in Aceh Besar, selected purposively as the sample of this research. The instruments used in this research are questionnaire and direct observation in the field, while the observed variables are: farmer characteristics, farmer knowledge and artificial insemination result. The results of this research revealed that the characteristics and knowledge of the farmers were good and showed a real relationship to the successfulness of AI in Aceh Besar Districts. The average service per conception (S / C) in Aceh Besar Districts during 2017 was 1.32 while the conception rate (CR) was 86.36%. The results were in accordance with the standard of general guidance of Upsus Siwab Year 2017.
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