Managers of federal, state, local, and nonprofit organizations around the world are faced with the complex task of managing interconnected systems of scarce resources. One key example of this has been the recent research on the connections between water, energy, and food/agriculture, and the problem of managing these resources to be sustainable and reduce the likelihood of resource depletion. While engineering research has focused on achieving greater efficiencies in resource management, less attention has been given to issues of governance within the fragmented, decentralized, and polycentric systems that are responsible for resource delivery. The central question animating this paper is whether resource management decisions in water, energy, and food are siloed, and what theoretical frameworks can be leveraged to develop strategies to break down existing silos. Results from a survey of water agencies suggests that there is little communication between the water, energy, and food policy areas. If achieving greater nexus requires increased communication and repeated interactions, there is significant work to be done to re-think how policy and management are organized and conducted.

Managers of federal, state, local, and nonprofit organizations around the world are faced with the complex task of managing interconnected systems of scarce resources. One key example of this has been the recent research on the connections between water, energy, and food/agriculture, and the problem of managing these resources to be sustainable and reduce the likelihood of resource depletion. While engineering research has focused on achieving greater efficiencies in resource management, less attention has been given to issues of governance within the fragmented, decentralized, and polycentric systems that are responsible for resource delivery. The central question animating this paper is whether resource management decisions in water, energy, and food are siloed, and what theoretical frameworks can be leveraged to develop strategies to break down existing silos. Results from a survey of water agencies suggests that there is little communication between the water, energy, and food policy areas. If achieving greater nexus requires increased communication and repeated interactions, there is significant work to be done to re-think how policy and management are organized and conducted.

Managers of federal, state, local, and nonprofit organizations around the world are faced with the complex task of managing interconnected systems of scarce resources. One key example of this has been the recent research on the connections between water, energy, and food/agriculture, and the problem of managing these resources to be sustainable and reduce the likelihood of resource depletion. While engineering research has focused on achieving greater efficiencies in resource management, less attention has been given to issues of governance within the fragmented, decentralized, and polycentric systems that are responsible for resource delivery. The central question animating this paper is whether resource management decisions in water, energy, and food are siloed, and what theoretical frameworks can be leveraged to develop strategies to break down existing silos. Results from a survey of water agencies suggests that there is little communication between the water, energy, and food policy areas. If achieving greater nexus requires increased communication and repeated interactions, there is significant work to be done to re-think how policy and management are organized and conducted.

This paper focuses on regional integration through the lenses of the Water&ndash:Food&ndash:Energy (WEF) nexus, a concept putting strong emphasis on cross-sectoral and multi-level interactions as well as on resource interdependencies. There is an extensive amount of published research focusing on the Aral Sea basin. In this paper, the authors build upon these different contributions and provide a meta-analysis of the literature of WEF nexus opportunities in Central Asia (CA) countries. This paper contributes to ongoing discussions regarding how the WEF Nexus can represent an opportunity for reinforced collaboration regarding resources management. To do so, focusing on existing literature, this paper first (1) explores how the nexus can be a relevant instrument for regional integration. Second (2), it provides an overview of water, food, energy conditions and challenges in the Aral Sea basin in particular. Third (3), synthesizing existing research, the authors identify critical variables to be considered as hurdles or leverage points for WEF nexus implementation in the Aral Sea basin. Finally (4), we go back to our initial set of questions and identify some possible avenues for future research.

This paper focuses on regional integration through the lenses of the Water–Food–Energy (WEF) nexus, a concept putting strong emphasis on cross-sectoral and multi-level interactions as well as on resource interdependencies. There is an extensive amount of published research focusing on the Aral Sea basin. In this paper, the authors build upon these different contributions and provide a meta-analysis of the literature of WEF nexus opportunities in Central Asia (CA) countries. This paper contributes to ongoing discussions regarding how the WEF Nexus can represent an opportunity for reinforced collaboration regarding resources management. To do so, focusing on existing literature, this paper first (1) explores how the nexus can be a relevant instrument for regional integration. Second (2), it provides an overview of water, food, energy conditions and challenges in the Aral Sea basin in particular. Third (3), synthesizing existing research, the authors identify critical variables to be considered as hurdles or leverage points for WEF nexus implementation in the Aral Sea basin. Finally (4), we go back to our initial set of questions and identify some possible avenues for future research.

The European Commission asked EFSA to update its previous Opinion on nickel in food and drinking water, taking into account new occurrence data, the updated benchmark dose (BMD) Guidance and newly available scientific information. More than 47,000 analytical results on the occurrence of nickel were used for calculating chronic and acute dietary exposure. An increased incidence of post-implantation loss in rats was identified as the critical effect for the risk characterisation of chronic oral exposure and a BMDL10 of 1.3 mg Ni/kg body weight (bw) per day was selected as the reference point for the establishment of a tolerable daily intake (TDI) of 13 μg/kg bw. Eczematous flare-up reactions in the skin elicited in nickel-sensitised humans, a condition known as systemic contact dermatitis, was identified as the critical effect for the risk characterisation of acute oral exposure. A BMDL could not be derived, and therefore, the lowest-observed-adverse-effect-level of 4.3 μg Ni/kg bw was selected as the reference point. The margin of exposure (MOE) approach was applied and an MOE of 30 or higher was considered as being indicative of a low health concern. The mean lower bound (LB)/upper bound (UB) chronic dietary exposure was below or at the level of the TDI. The 95th percentile LB/UB chronic dietary exposure was below the TDI in adolescents and in all adult age groups, but generally exceeded the TDI in toddlers and in other children, as well as in infants in some surveys. This may raise a health concern in these young age groups. The MOE values for the mean UB acute dietary exposure and for the 95th percentile UB raises a health concern for nickel-sensitised individuals. The MOE values for an acute scenario regarding consumption of a glass of water on an empty stomach do not raise a health concern.

Abstract The European Commission asked EFSA to update its previous Opinion on nickel in food and drinking water, taking into account new occurrence data, the updated benchmark dose (BMD) Guidance and newly available scientific information. More than 47,000 analytical results on the occurrence of nickel were used for calculating chronic and acute dietary exposure. An increased incidence of post‐implantation loss in rats was identified as the critical effect for the risk characterisation of chronic oral exposure and a BMDL10 of 1.3 mg Ni/kg body weight (bw) per day was selected as the reference point for the establishment of a tolerable daily intake (TDI) of 13 μg/kg bw. Eczematous flare‐up reactions in the skin elicited in nickel‐sensitised humans, a condition known as systemic contact dermatitis, was identified as the critical effect for the risk characterisation of acute oral exposure. A BMDL could not be derived, and therefore, the lowest‐observed‐adverse‐effect‐level of 4.3 μg Ni/kg bw was selected as the reference point. The margin of exposure (MOE) approach was applied and an MOE of 30 or higher was considered as being indicative of a low health concern. The mean lower bound (LB)/upper bound (UB) chronic dietary exposure was below or at the level of the TDI. The 95th percentile LB/UB chronic dietary exposure was below the TDI in adolescents and in all adult age groups, but generally exceeded the TDI in toddlers and in other children, as well as in infants in some surveys. This may raise a health concern in these young age groups. The MOE values for the mean UB acute dietary exposure and for the 95th percentile UB raises a health concern for nickel‐sensitised individuals. The MOE values for an acute scenario regarding consumption of a glass of water on an empty stomach do not raise a health concern.