Pathological studies on urea poisoning in milk goats
1982
Kim, S.B. (Gyeongsang Nat'l Univ., Jinju (Korea R.). Coll. of Agriculture, Dept. of Veterinary Medicine) | Chung, U.I. (Office of Rural Development, Anyang (Korea R.). Inst. of Veterinary Research)
Pathological studies on 6 milk goats administered with urea were carried out to determine the effects of acute and chronic poisoning on the animal. Clinical signs appeared about 10 minutes after ingestion of the urea and they consisted chiefly in dullness, staggering, uncontrolled urination, dyspnoea, frothy salivation, bloating, muscular tremor, humping of back and tetanic spasms. Macroscopic lesions were failure of blood clot, frothy and bloody contents in the highly congested respiratory tract, pulmonary edema, rumenitis and abomatitis accompanying with petechiation of the upper small intestine. Microscopically, the liver showed vacuolar degeneration, fatty change and areas of necrosis and partial proliferation of the interlobular connective tissues in chronic cases. The renal epithelium displayed vacuolar degeneration, necrosis and hyaline casts in their lumens. In the lungs, there were hyperemia, edema, hemorrhages, and acute catarrhal bronchitis. Neuronal degeneration and necrosis in the central nervous system, cattarhal rumenitis, abomatitis, doudenitis and myocaridal hemorrhage were also demonstrated
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