Safety and immunogenicity on the inactivated infectious bovine rhinotracheitis (IBR) - bovine viral diarrhea (BVD) - parainfluenza type-3 (PI3) vaccine
1988
Kim, D.W. | Park, B.K. | Yoo, H.S. | Heo, Y. | Kim, Y.H. (Rural Development Administration, Anyang (Korea R.). Veterinary Research Inst.) | Kwon, H.J. (Bayer Veterinary Research Inst., Seoul (Korea R.))
An experimental combined vaccine containing inactivated infectious bovine rhinotracheitis (IBR) virus, bovine viral diarrhea (BVD) virus and parainfluenza-3 (PI3) virus was developed, and evaluated for its safety and immunogenicity in laboratory animals, goats and calves. The combined vaccine was proved safe in mouse, guinea pig and calf. In immunogenicity test, guinea pigs, goats and calves given the combined vaccine produced significant immune responses a1015gainst IBR, BVD and PI3 respiratory diseases in f
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