Nitrates and nitrites and the utilization of beta-carotene. Pt. 1. Effect of different amounts of nitrates and nitrites in the diet on the utilization of beta-carotene by rat organism
1990
Majchrzak, D. | Gronowska-Senger, A. (Szkola Glowna Gospodarstwa Wiejskiego - Akademia Rolnicza, Warszawa (Poland). Instytut Zywienia Czlowieka)
Two biological experiments lasting 30 days were carried out on male Wistar rats standardized with respect to hepatic vitamin A content. The animals were given orally 30 mcg daily an oil solution of beta-carotene and diets with varying amounts of potassium nitrate (0.5; 1.0; 2.0; 4.0; 6.0 per cent) and sodium nitrite (0.05; 0.1; 0.5; 1.0 per cent). Nitrates and nitrites in diets reduced the utilization of beta-carotene in a dose dependent way. The nitrate reduced the utilization of provitamin by from about 50 per cent to over 60 per cent and the nitrite reduced it by from over 60 per cent to about 80 per cent. The studied compounds exerted also a negative effect on the consumption of diet and weight gain
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