Lysine production in industrial scale
1992
Gal, F. | Balogh, I.
The first Hungarian lysine factory was built by a Japanese firm at Kaba in 1992. The nominal capacity of the factory is 5000 t/year but presently the factory is working at a pace of 6000 t/year. The factory uses molasses as a culture medium for a special strain of Corynebacterium glutamicum. This strain doesn't need methionine and threonine in the medium which makes the production easier and cheaper. The biggest problem is the uneven quality of the molasses which makes it difficult to dissolve it precisely to the required concentration. After a fermentation process the pH is lowered to 1.5 and the lysine is absorbed by an ion-exchanger. The liquid that leaves the ion-exchanger contains a lot of bacteria, a good source of nutrition for animals or plants. The pH of the liquid is reset then it is dried until the extract content reaches 40. This product can be used as feed supplement or, more typically, as a biofertilizer. The lysine is eluated from the ion-exchanger resin by ammonia. The eluate goes through a vacuum condenser then a centrifugal drier. Finally the crystallized lysine is dried and packed
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