Anatomical, developmental and immunocytochemical aspects of the porcine hypothalamo-hypophyseal-gonadal axis
1993
Molenaar, G.J. (University of Utrecht, Utrecht (Netherlands). School of Veterinary medicine)
The effect of the neonatal testosterone peak on hypothalamic differentiation has been studied after experiments involving testosterone depletion and suppletion. The cytoarchitecture of the alleged homologue of the human SDNMPOA (sexual dimorphic nucleus of the medial preoptic area) has been studied in male and female controls and was compared with that in experimental animals which neonatally gonadectomized and/or had received T implants. The animals were sacrificed at the age of 38 weeks. Sexual dimorphism appeared to become apparent no sooner than at two years of age. Moreover, the nucleus consisted of vasopressin and oxytocin containing cells unlike the human or rodent homologues
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