Total parenteral anesthesia with medetomidine-buprenorphine-midazolam combination in dogs: preliminary characterization | Anesthesie parenterale totale avec l'association medetomidine-buprenorphine-midazolam chez le chien: caracterisation preliminaire
1997
Pypendop, B. | Verstegen, J. (Liege Univ. (Belgium). Faculte de Medecine Veterinaire. Service d'Obstetrique et des Troubles de la Reproduction. Section des Petits Animaux)
The clinical effects of a parenteral anesthetic combination based on medetomidine, buprenorphine and midazolam administration were characterized in dogs. Moreover, the reversibility of this combination by atipamezole was studied. An anesthetic stage was induced in all treated dogs, characterized by an immobilization, an absence of reaction to noise and pain stimulation, a muscle relaxation, and a decrease in heart rate, respiratory rate and rectal temperature. An atipamezole administration allowed to a rapid reversal of these effects. In a control group, in which saline was given in place of medetomidine, sedation was never observed. The study protocol seems to represent an alternative to other parenteral anesthesias for short to medium duration procedures in dogs.
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