Marker assisted selection in livestock. 1st paper: Theoretical aspects
1997
Fesus, L. (Allattenyesztesi es Takarmanyozasi Kutatoint., Herceghalom (Hungary))
Following the discussion of theoretical aspects of the traditional selection methods the article identifies the limits of these methods. Particular attention is paid to the discussion of occasional inbreeding and its consequences (more frequent occurence of genetic disorders). Problems related to multi-trait selection are discussed as well. In the future the application of marker assisted selection (MAS) using DNA markers can improve selection efficiency. Author gives detailed information on markers, identification of QTL-s, possible areas using MAS, possible difficulties and the situation to be expected in the future. Role of microsatellites is discussed as well as the nature of Type I and Type II molecular genetic markers. Problems related to the use of patented primers and/or procedures are mentioned too. Other possible applications of genetic markers in animal breeding are also discussed (study genetic structure of populations, testing homozygosity of inbred lines, estimation inbreeding in populations, maintaining gene reserve populations, parentage control, genetic distance studies, planning crossbreeding experiments)
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