The influence of LHRH and synthostigmin on acetylcholinesterase (ACHE)-positive innervation of the rat thymus
1998
Dorko, F. | Kocisova, M. | Miklosova, M. (P.J. Safarik Univ., Kosice (Slovak Republic). Faculty of Medicine)
The administration of LHRH (luteinising hormone-releasing hormone) results in macroscopic and microscopic regeneration of atrophied thymi in old rats. The distribution and density of ACHE-positive nerves in the regenerated thymi resembled the innervation in the pre-involution developmental stages. The ACHE-positive nerves were abundant also in the functioning parenchyma of the regenerated thymi. The administration of a parasympathomimetic drug synthostigmin failed to regenerate the atrophied thymi and no ACHE-positive nerve structures were present in the preserved parts of the thymus parenchyma
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