Stress-reactive response of the pineal gland of senile rats
1996
Milin, J.R. (Medical Faculty, Novi Sad (Yugoslavia). Institute of Pathology and Histology)
The reactive response of pinealocytes and glia cells to an acute immobilization was studied. Freely moving rats: Pinealocytes plurality was recognized as bright and dusk cells - morphofunctional variants of a single cell. Their domination was the criterion to consider bright cells the pinealocytes of basal activity. Dusk cells were regarded as previously functionally aminated cells, or their post-secretory forms, whose progress into the stage of stimulated activity was interrupted. The presence of degenerating cells indicated that the pinealocytes were subjected to an aged programmed degeneration and elimination. The structural fashion indicated an active role of glia cells in pinealocyte physiology. Stress-affected rats: The stress-reactive response was marked by functional animation of the most of pinealocytes of basal activity. The rate occurrence of dusk and degenerating pinealocytes was unchanged. Glia cells were characterized by a cavern-like destruction of cytoplasm, whose expansion treathened with cell elimination. In sum, the prevalence of the functionally animated cells indicated that the pinealocytes retained their ability to meet stress-induced secretory demands in deep senility, while stress seemed to be detrimental to both pinealocytes and glia cells.
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