Cellular contribution of the different regions of the somatopleure to the developing limb
1994
Geduspan, J.S. | Solursh, M. (Philippines Univ. in the Visayas, Leganes, Iloilo (Philippines). Coll. of Arts and Sciences)
Regionalization of the presumptive limb region was examined before and at the onset of limb development by means of a variety of transplantation experiments between the quail and chick embryos in ovo. The results demonstrated a two-step process, the first of which was the designation of the region of the somatopleure that would become part of the limb, followed by specification of dorsal and ventral regions of the limb. The second process relates to changes in the ability of the somatic ectoderm to undergo extensive lateral displacement with development. The positional determination of the dorsal and ventral properties of the medial and lateral ectoderms of the prospective limb region and their distal displacement during limb outgrowth may be important morphogenetic events in limb development
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