Effects of humine compounds on iodine utilisation and retention and on the function of the thyroid gland
2001
Herzig, I. | Pisarikova, B. | Bendova, J. (Vyzkumny Ustav Veterinarniho Lekarstvi, Brno (Czech Republic)) | Kursa, J.
Effects of sodium humate (HuNa), containing 61.9 % of humic acids in dry matter, on utilisation and retention of dietary iodine were investigated in balance experiments carried out in pigs. The experimental group was fed a diet supplemented with 3 % of HuNa. The daily intake of iodine was 4.45 microg per kg live weight (4.08 microg per kg live weight in the control group). The supplementation of HuNa increased significantly the amount of iodine excreted in faeces (53.2 +/- 11.0 vs. 43.0 +/- 6.47 microg per animal per day). Compared with controls, the HuNa group showed significantly higher triiodothyronine concentration and nonsignificantly lower thyroxine and iodine concentrations in blood serum. Dietary iodine utilisation was lower in the HuNa than in the control group (62.3 vs. 66.6 %). The results show that utilisation of dietary iodine was limited and that sodium humate (humic acids) reduced iodine utilisation and retention and affected also other parameters indicating their goitrogenic effects.
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