Reproductive disturbance caused by an S-triazine herbicide in pigs
1999
Gojmerac,T. | Uremovic,M. | Uremovic,Z. | Curic,S. | Bilandzic,N.
The effect of subacute treatment with a low concentration of atrazine (an s-triazine herbicide) on endocrine oestrus regulation in gilts was determined.A group of nine gilts (F1 generation of Swedish Landrace X Large Yorkshire) were treated with 1 mg atrazine/kg body mass daily, mixed to the feed for 19 days before the onset of expected oestrus.Blood samples were obtained by cranial vena cava puncture three times daily at 3-h intervals on five post-treatment days, i.e. before and during oestrus.The serum concentration of oestradiol-17beta (E2) was determined by the fluoroimmunochemical method.On day 2 before the onset of expected oestrus, a significantly lower (P0.001) E2 concentration was measured in the serum of treated gilts (31.25+-1.95 and 39.32+-1.38 pg/ml) than in untreated control pigs (51.43+-1.29 and 68.59+-2.99 pg/ml).
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