Molecular biology of feline coronaviruses
1999
Kiss,I. | Kecskeméti,S. | Tanyi,J. | Klingeborn,B.S. | Belák,S.
The authors give a short review on contemporary knowledge about the molecular biology of feline coronaviruses. Particular attention is paid to the connection between feline enteric coronaviruses (FECV) and feline infectious peritonitis viruses (FIPV).FIP is a leading infectious cause of death among young cats, and occurs worldwide. The disease has a progressive immune-mediated pathogenesis. Diagnosis and control of the disease is difficult since serological investigations are not informative for this purpose, and neither treatment nor reliable vaccines are available at present.FECV may produce mild enteritis, but most infections remain subclinical.However, FECV presents a considerable health risk to cats because it is the precursor of FIPV.
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