Age- and sex-determined differences in the establishment of tetanus antitoxin reproduction in guinea-pigs

Rethy, A. L.; Geresi, Magdolna; Rethy, L.

Age- and sex-determined differences in the establishment of tetanus antitoxin reproduction in guinea-pigs

2001

Rethy, A. L. | Geresi, Magdolna | Rethy, L.

The tetanus immunisation results obtained in the two sexes, were compared in animal models. Complete immunisation series of weaned, adult and aged guinea-pigs were performed with aluminium phosphate adsorbed purified tetanus toxoid as well as with typhoid-tetanus vaccine (TY-TE) containing lipopolysaccharide. The results were in accordance with our previous observations in humans. Tetanus immunisation series on guinea pigs it can be concluded that TAT may be influenced by the effects of sex chromosomes as well as of sexual hormones.

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