Effects of Protaetia Orientalis (Gory et Perchlon) Farva on the Lipid Metabolism in Ethanol Administered Rats
2000
Kang Il-Jun | Kim Ha-Kyung Division of Life Sciences, Hallym University, Chunchon 200-702 (Korea Republic)
This study was designed to determine the effects of Protaetia Orientalis larva (Gory et Perchlon) on the in vivo lipid metabolism in Sprague Dawley rats administered with ethanol to induce damage in the liver. The administration of ethanol resulted in the increase of serum triglyceride and total cholesterol, atherogenic index, serum GOT and GPT, and liver triglyceride of the experimental rats. On the other hand, those parameters of the rats fed in combination with ethanol and Protaetia Orientalis larva (Gory et Perchlon) have decreased. Ethanol feeding resulted in decrease of HDL-cholesterol, whereas that of the rats fed in combination with ethanol and Protaetia Orientalis larva (Gory et Perchlon) was increased. Ultrastructural examination of hepatocytes of ethanol administerde rats showed increased lipid droplets. However, lipid droplets of those fed in combination with ethanol and Protaetia Orientalis larva were reduced in number and the size.
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