Hypertriglyceridemia in rats induced by consumption of a food-derived carcinogen,2-amino-1-methyl-phenylimidazo(4,5b)pyridine (PhIP)
1999
Isimura, Y. (Hiroshima Univ. (Japan)) | Watanabe, H. | Kato, N. | Yanagita, T. | Wakabayashi, K.
2-Amino-1-methyl-phenylimidazo[4,5b]pyridine (PhIP), the most abundant mutagenic heterocyclic amine produced in cooked meat and fish, is known to be a carcinogen for rats and mice. This study provides the first evidence for hypertriglyceridemia in rats exposed to PhIP, suggesting its potential risk to induce not only carcinogenesis, but also atherosclerosis, and highlighting the potential importance of PhIP for humans
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书目信息
页码
pp. 1634-1636
其它主题
Substance cancerigene; Carcinogenos; Hyperlipidemie
语言
英语
注释
Summary (En)
1 table; 1 fig.; 14 ref
类型
Summary
2001-08-15
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