Blood biochemistry of rabbits after intravenous inoculation of unilocular hydatid cyst fluid of sheep origin
2000
Anwar, Z. | Tanveer, A. (Punjab Univ., Lahore (Pakistan). Dept. of Zoology)
Unilocular, hydatid cyst fluid of sheep origin was inoculated to five group of rabbits. The doses given were (1) Crude Low Dose (CLD), (2) Filtered Low Dose (FLD), Crude Medium Dose (CMD), (3) Filtered Medium Dose, (FMD) and (4) High Dose (HD of filtered hydatid cyst fluid). Control group was inoculated with similar doses of distilled water. Blood samples were pooled fortnightly and biochemical analysis made were glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT) bilirubin, glucose, and plasma protein content. To face stress conditions through energy production, all the groups showed elevation in their GOT, PT activities and depletion in glucose and protein contents of blood. High dose group, however, behaved differently, which showed depletion in both of these transaminases, probably due to interference in the synthesis or post synthetic destruction of these enzymes. Bilirubin content increased significantly only in the "high dose" group probably due to enhanced degradation of haemoglobin content.
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