Accumulation of minerals in an organism of antidote-supplemented sheep during industrial copper intoxication
2000
Elgerwi, A. | Bires, J. | Britan, M. | Hiscakova, M. | Huska, M. (University of Veterinary Medicine, Kosice (Slovak Republic). Dept. of Internal Diseases of Ruminants and Swine)
Diagnostics of experimental copper intoxication by industrial emission from a copper factory on the basis of accumulation and distribution of Cu, Zn, Fe, Mo, Se, As, Cd and Pb in blood serum and organs was evaluated in relation to administration of ammonium molybdate and sodium sulphate. An increase in cupremia in comparison with the starting values was recorded in both groups of sheep on day 17 while maximum concentrations were determined at the end of the experiment. No significant differences in cupremia in relation to administration of ammonium molybdate and sodium sulphate were observed between the A and B groups. With risk elements, the highest concentration of Cu was found in the liver in both groups A and B. Significantly higher (p0.05) Fe content was determined in bones and uterus in group B. The Mo content was increased in the kidneys (p0.05) and bones (p0.01) in group A. Additional differences in the dynamics of Fe, Se, As, Cd, and Pb, observed in the blood serum and organs of sheep from groups A and B during industrial intoxication with copper, were not unambiguously related to the application of ammonium molybdate and sodium sulphate and resulted probably from interactions which occured during the processes of resorption, intermediary metabolism and excretion between the minerals present in the emission
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