Preventive action of fumagillin on the degree of infection with Nosema apis in the digestive tract of bees
2000
Mladjan, V. (Institute of Veterinary Medicine of Serbia, Belgrade (Yugoslavia)) | Todorovic, D. | Lolin, M.
The presence of Nosema apis in the digestive tract of bees and the preventive effect of fumagillin on their appearance were investigated pathohistologically. Three groups of bees were formed. Group A was artificially infected with Nosema apis spores in sugar syrup. In parallel with the infection the bees of Group B - were admistered sugar syrup containing 0.015 g Fumagillin DCH. Group C was not artificially infected and served as a control. Organs such as the crop, midgut, small intestine, Malpighian tubes, rectum, and rectal papillae were taken from all three groups 4, 9, 12, and 16 days following artificial infection. It was established that Nosema apis parasites were localized exclusively in the epithelial cells of the midgut and that fumagillin had a preventive effect by slowing down parasite development and stabilizing the system of peritrophic membranes.
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