Comparison of estimated breeding values and daughter yield deviations used in segregation and linkage analyses
2002
Freyer, G. | Kuehn, C. (Research Inst. for the Biology of Farm Animals, Dummerstorf (Germany)) | Stricker, C.
Estimated breeding values (EBVs) and daughter yield deviations (DYDs) were used in a segregation and linkage analysis of milk, fat and protein yield. The results were compared focusing on differences in estimated recombination rates and test criteria after using both trait measures. Data analysis was based on a grand daughter design including 591 sons of 5 sires. The sons were typed for several microsatellite markers on chromosome 6. Low additive quantitative trait locus (QTL) effects were obtained from analyses using DYDs. The estimated recombination rates were similar if the QTL effects could be estimated with high accuracy whether EBVs or DYDs were used. A likelihood odds ratio (LOD) score 3.12 (EBV) and 2.15 (DYD) was obtained for fat yield. The recombination rate was zero between QTL and one marker on chromosome 6 in both cases. For protein yield the LOD scores were 1.78 (EBV) and 1.76 (DYD) while estimating a recombination rate of 0.06 each. If QTL effects are estimated with sufficient accuracy, the results of analyses based on EBVs can provide a good indication of linkage between genetic markers and QTL for sons with a high number of tested daughters included.
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