Effects of Houttuynia cordata Thunb on Lipidperoxide and Cholesterol in 2,3,7,8-TCDD-damaged Rats
2003
Ha, B.J. | Ha, J.M. | Lee, S.H. | Lee, J.H. (Sila University, Busan, Republic of Korea) | Kim, M.S. (Thunb Foundation and Namdonongsan, Sangcheon, Republic of Korea)
TCDD, one of the notorious toxic environmental pollutants, damages various organs including liver and is regarded as an endocrine disrupter. To investigate the effects of Houttuynia cordata Thunb on the biochemical parameters of function, liver and serum of TCDD-treated rats were used. Seven days after the injection of TCDD , HCT was administered to rats on every other day for four weeks. The lipidperoxide activity was examined by measuring the level of total cholesterol, HDL-cholesterol, LDL-cholesterol, total lipid and triglyceride in serum, and malondialdehyde in liver tissue of rats. Results showed that lipidperoxidation was inhibited in the significant level when 2,3,7,8-TCDD -damaged rats were treated with HCT.
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