Wound healing and antimicrobial activity of formulated cream of leaf volatile oil of Atalantia monophylla Correa.
2002
Manimaran, S. | Loganathan, V. | Akilandeswari, S. | Jaswanth, A. | Sathya, S. | Ruckmani, K. (Periyar Coll. of Pharmaceutical Sciences for Girls, Tiruchirapalli (India))
Effect of formulated cream of leaf volatile oil of Atalantia monophylla Correa. for wound healing and antimicrobial activity (bacteria and fungi) were evaluated. The volatile oil was distilled from leaves by using hydrodistillation method. The 2% and 5% cream was prepared by using base (stearic acid, potassium hydroxide, cetostearyl alcohol, liquid paraffin, petroleum jelly, propyl paraben sodium, methyl paraben sodium and glycerin). The cream showed very good wound healing activity by excision wound method in rats compared to that of standard drug Nitrofurazone. The antimicrobial activity of 2% formulated cream was also carried out by standard cup plate technique using Ciprofloxacin and Nystatin as standard drugs for bacteria and fungi respectively.
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