Electrophoretic analysis of serum proteins in dogs naturally infected with heartworm or Ehrlichia canis
1997
Supot Wattanapansak | Meena Sarikaputi | Boonlert Prechatangkit | Athipoo Nuntaprasert
Using cellulose acetate electrophoresis, sera from 26 uninfected (control) dogs, 51 dogs infested with heartworm and 8 dogs infected with Ehrlichia canis, could be separated into albumin, alpha-1-globulin, alpha-2-globulin, beta-globulin and gamma-globulin. No difference in total serum protein concentration in male and female was observed uninfected dogs but levels of albumin, alpha-2-globulin and A:G ratio in younger dogs were higher than those of older dogs (P0.05). Levels of albumin, alpha-2-globulin and A:G ratio in dogs infested with heartworm were lower than those of the uninfected group. It was found that 40 percent of dogs with heartworm showed a much higher level of beta-globulin than that of the control group. In dogs infected with E. canis, albumin levels and A:G ratio were lower but alpha-1-globulin was higher when compared with those of uninfected dogs (p0.05). However, 2 dogs in the E. canis infected group showed a much higher level of gamma-globulin. It is concluded that there were changes in serum protein components in dogs with heartworm or E. canis although those changes were not specific to each type of infection. Dogs infested with heartworm showed the tendency of having a high level of beta-globulin.
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