The effects of vitamin E and selenium on arginase activity in cypermethrin administered rats
2004
Benzer, F.
This study was carried out to determine the effects of vitamin E and selenium on arginase activities in cypermethrin administered rats. 30 female Wistar Albino rats weighting 180-250 g were used in this study. The rats were divided into five equal groups. The first group was fed placebo and the second group was given cypermethrin for 5 days. To the groups 3, 4 and 5 prior to cypermethrin administration, vitamin E, selenium and both vitamin E and selenium respectively were administered for 3 days. Arginase activity was spectrophotometrically measured using the Thiosemicarbazide Diacetyl Monoxime Urea method. Cypermethrin administration did not change arginase activity in any of the tissues. Prior to cypermethrin administration, administration of vitamin E and selenium alone or as combination decreased the arginase activity in liver and kidney tissues and increased in brain and heart tissues compared to controls. Vitamin E, selenium and vitamin E + selenium combination increased the activity of arginase in several tissues in the same way
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