Postnatal development of blood serum concentrations of immunoglobulin IgG, IgA and IgM isotypes in suckling foals
2006
Sedlinska, M.(Veterinarni a Farmaceuticka Univ., Brno (Czech Republic)) E-mail:[email protected] | Krejci, J.(Vyzkumny Ustav Veterinarniho Lekarstvi, Brno (Czech Republic)) | Vyskocil, M.(Veterinarni a Farmaceuticka Univ., Brno (Czech Republic)) | Kudlackova, H.(Vyzkumny Ustav Veterinarniho Lekarstvi, Brno (Czech Republic))
Postnatal changes in concentrations of immunoglobulin IgG, IgM and IgA isotypes from birth until the age of five months were monitored by the ELISA method. The experiment was performed in a group of 52 thoroughbred foals and their mothers. Among the studied animals, failure of colostral immunity transfer was recorded in only four foals (7.7 percent). The concentrations of immunoglobulin IgG and IgA isotypes primarily decreased during the first weeks of life and then gradually increased until the end of the investigated period. Immunoglobulin IgG isotype concentrations reached the values of adult animals by the end of the investigated period, whereas immunoglobulin IgA isotype concentrations did not reach the values of adult horses during the whole studied period. Immunoglobulin IgM isotype concentrations increased rapidly from birth onwards. The beginning of active antibody formation was inversely proportional to the level of colostral immunoglobulins.
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