Expression of galectin-3 in rat brain
Lee, Y.K.(Seoul National University, Seoul, Republic of Korea) | Kang, H.E.;Woo, H.J.(Korea Food and Drug Administration, Seoul, Republic of Korea)E-mail:hjwoo@snu.ac.kr
Galectin family, endogenous β-galactoside-binding animal lectins, is known for the role in cell differentiation, morphogenesis, apoptosis and tumorigenesis. Galectin-3, one of family member, has been studied for its role in cell differentiation and tumor metastasis, and for its expression on epithelial cells of colon and mast cells but not in brain. Several reports, however, suggest its expression in brain including as a prion binding protein. In this report we explored possibility of galectin-3 expression in brain tissue.
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