Expression of osteopontin in developing mouse brain
Kim, G.B.;Hwang, I.S.;Moon, C.J.;Shin, T.K.;Jee, Y.H.(Cheju National University, Jeju, Republic of Korea)E-mail:yhjee@cheju.ac.kr | Son, H.Y.(Chungnam National University, Daejeon, Republic of Korea)
This study was undertaken to examine the developmental expression of osteopontin(OPN) in the mouse brain. In Western blotting analysis, the expression of OPN was noted initially at embryonic stage and increased gradually after birth and decreased at postnatal day 60(P60). In immunohistochemistry, OPN expression was found in the interstitial nucleus Cajal and the substantia nigra reticularis in anterior part of the brain and in the inferior olivary complex, the parabrachial nucleus, the facial nucleus, the gigantocellular reticular nucleus, the trigeminal nucleus and the anterior interposed nucleus in posterior part of the brain at P31 and P60.
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