Phenolic Compounds from Barks of Actinidia arguta Planchon Growing in Korea and its Anti-Oxidative and Nitric Oxide Production Inhibitory Activities
2005
Lim, H.W. (Chung-Ang University, Seoul, Republic of Korea) | Shim, J.G. (Chung-Ang University, Seoul, Republic of Korea) | Choi, H.K. (Chung-Ang University, Seoul, Republic of Korea) | Lee, M.W. (Chung-Ang University, Seoul, Republic of Korea), E-mail: mwlee@cau.ac.kr
Phytochemical examination of the barks of Actinidia arguta led to the isolation of five flavonoids. Structures of compounds were elucidated as catechin (1), (-)-epicatechin (2), quercetin (3), quercetin-3-O-β-D-glucopyranoside (4), quercetin-3-O-β-D-galactopyranoside (5) by comparison with previously reported spectral evidences. To investigate the anti-oxidative effect and nitric oxide (NO) production inhibitory activity of these compounds, DPPH radical scavenging activity and nitric oxide production inhibitory activity in IFN-γ, LPS stimulated RAW 264.7 cell were examined.
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