Effects of Dietary Methionine and Folate Supplementation in Ethanol-Fed Rats
2006
Mun, J.A. (Hannam University, Daejeon, Republic of Korea) | Min, H.S. (Hannam University, Daejeon, Republic of Korea), E-mail: [email protected]
Chronic alcohol consumption is associated with perturbation of hepatic metabolism of sulphur-containing amino acid. The goal of present study was to evaluate the influence of dietary supplementation of methionine or folate to chronically ethanol-fed rats on the metabolism of sulfur-containing amino acids and one-carbon metabolism. Sprague Dawley male rats were fed Lieber-Decarli liquid diet with 0% ethanol (control), 36% ethanol (E), 36% ethanol combined with methionine supplement (EM) or folate supplement (EF) for 8 weeks.
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