Purification and Properties of HPS (Halitosis Prevention Substance) Isolated from Cumin (Cuminum cyminum L.) Seed
2005
Kang, E.J. (Wonkwang Health Science College, Iksan, Republic of Korea) | Ryu, I.H. (Wonkwang University, Iksan, Republic of Korea), E-mail: [email protected] | Lee, K.S. (Wonkwang University, Iksan, Republic of Korea)
Halitosis is mainly caused by the presence of volatile sulfur-containing compounds (VSC's) produced by proteolytic periodontopathic bacteria in the oral cavity. Various mouth-rinses have been offered on the market as solutions to reduce halitosis. The aim of this study was to find a potent substance for the prevention of halitosis. The halitosis prevention substance (HPS) from cumin seed powder was purified by solvent extraction, silica gel column chromatography and preparative TLC to yield an oil phase (0.98%).
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