Accelerating Effect of TNF-α on the Rhus verniciflua-induced Growth Inhibition and Apoptosis in Human Osteosarcoma Cells
2005
Kim, H.D. (Chonbuk National University, Chonju, Republic of Korea) | Kook, S.H. (Chonbuk National University, Chonju, Republic of Korea) | Kim, B.T. (Chonbuk National University, Chonju, Republic of Korea) | Kim, J.G. (Chonbuk National University, Chonju, Republic of Korea) | Jeon, Y.M. (Chonbuk National University, Chonju, Republic of Korea) | Lee, J.C. (Chonbuk National University, Chonju, Republic of Korea), E-mail: [email protected]
Previously, a flavonoid fraction, which consisted mainly of protocatechuic acid, fustin, fisetin, sulfuretin, and butein, here named RCMF [Rhus verniciflua Stokes (RVS) chloroform-methanol fraction], was prepared from a crude acetone extract of RVS which is traditionally used as a food additive and as an herbal medicine. In the present study, we investigated the effects of TNF-α on RCMF-induced growth inhibition and spoptosis inductino using human osteosarcoma (HOS) cells.
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