Niacin Upper Level Recommendation and Exposure Assessment of Foods and Multivitamin drugs
2005
Park, S.H. (National Institute of Toxicological Research, Seoul, Republic of Korea) | Lee, H.M. (National Institute of Toxicological Research, Seoul, Republic of Korea) | Yoon, E.K. (National Institute of Toxicological Research, Seoul, Republic of Korea) | Min, C.S. (National Institute of Toxicological Research, Seoul, Republic of Korea) | Kim, H.J. (National Institute of Toxicological Research, Seoul, Republic of Korea) | Jun, E.A. (National Institute of Toxicological Research, Seoul, Republic of Korea) | Ze, K.R. (National Institute of Toxicological Research, Seoul, Republic of Korea)
Niacin (vitamin B₃) is the generic term for nicotinic acid (pyridine 3-carboxylic acid) and nicotinamide (nicotinic acid amide), and coenzyme forms of the vitamin. Large doses of nicotinic acid are associated with a number of adverse effects in human. The effects include flushing, skin itching, nausea, vomiting and gastrointestinal disturbance. This study was conducted to estimate daily intake of niacin by ingestion of food and multivitamin, and to identify risk value related with side effects, which can be caused by large dose intake in population having a typical lifestyle.
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