Comparison of sensitivity between yellowtail Seriola quinqueradiata and red sea bream Pagrus major to Nocardia seriolae
2006
Itano, T.(Ehime-ken. Fish Disease Control Center, Uwajima (Japan)) | Nakaoka, N. | Kawakami, H. | Kono, T. | Sakai, M.
The sensitivity of yellowtail Seriola quinqueradiata and red sea bream Pagrus major to Nocardia seriolae was investigated. The LDsub(50) for yellowtail and red sea bream after being injected with N. seriolae was 1.1 x 10E3 CFU /100 g B.W. and 3.4 x 10E4 CFU/100 g B.W., respectively. In an immersion challenge, the LDsub(50) for yellowtail was 1.2 x 10E4 CFU/mL, while no mortality was observed in red sea bream at 1.0 x 10E5 CFU/mL for 26 days. These data indicate that yellowtail is more sensitive to the bacterium than red sea bream. Serum bactericidal activity against N. seriolae was not observed in both fish species. Production of superoxide anion in kidney phagocyies isolated from red sea bream significantly increased in response to addition of live N. seriolae. However, such increase of superoxide anion production was not detected in yellowtail kidney phagocytes. This suggests that superoxide anion from phagocytes is one of important factors in protection against nocardiosis.
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