Effect of Meal Pattern on Lipogenesis and Lipogenic Enzyme Activity in Rat Adipose Tissue Fed High Fat Diet
2006
Lee, J.J. (Chosun University, Gwangju, Republic of Korea) | Choi, H.S. (Chosun University, Gwangju, Republic of Korea) | Jeong, E. (Chosun University, Gwangju, Republic of Korea) | Choi, B.D. (Gyeongsang National University, Jinju, Republic of Korea) | Lee, M.Y. (Chosun University, Gwangju, Republic of Korea), E-mail: [email protected]
This study was undertaken to investigate the effects of meal pattern on lipogenesis and activities of lipogenic enzyme in rats epididymal and mesenteric adipose tissues. A high fat diet was fed either ad libitum or in l meal during the last 3 h of the dark cycle for 4 weeks. Lipogenesis was measured as glucose conversion to total lipid and activities of glucose-6-phosphate dehydrogenase (G6PDH), 6-phophogluconate dehydrogenase (G6PDH) and NADP-malate dehydrogenase (ME) were determined by measuring NADPH production.
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