Metabolic Flux Analysis of Beijerinckia indica for PS-7 Production
2005
Wu, J.R. (Pukyong National University, Busan, Republic of Korea) | Son, J.H. (Pukyong National University, Busan, Republic of Korea) | Seo, H.J. (Pukyong National University, Busan, Republic of Korea) | Kim, K.H. (Pukyong National University, Busan, Republic of Korea) | Nam, Y.K. (Pukyong National University, Busan, Republic of Korea) | Lee, J.W. (Dong-A University, Busan, Republic of Korea) | Kim, S.K. (Pukyong National University, Busan, Republic of Korea), E-mail: [email protected]
In order to investigate central metabolic changes in Beijerinckia indica, cells were grown on different carbon sources and intracellular flux distributions were studied under varying concentrations of nitrogen. Metabolic fluxes were estimated by combining material balances with extracellular substrate uptake rate, biomass formation rate, and exopolysaccharide (EPS) accumulation rate. Thirty-one metabolic reactions and 30 intracellular metabolites were considered for the flux analysis.
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