Prevalence and chemotherapy of nematode infestation in sheep
2001
Murtaza, G. (College of Veterinary Sciences, Lahore (Pakistan))
The present project was designed to find out the prevalence of nematodes and to evaluate the comparative efficacy of Albendazole, Levamisole and Oxfendazole against naturally occurring gastro-intestinal nematodes in sheep under field conditions in and around Bhakkar city. For this purpose the faecal samples of two hundred sheep were processed through carpological examination. Out of 200 sheep, 127 were found positive, so the prevalence of nematode was 63.5%. Out of positive animals 40 were randomly divided into four groups (10 sheep in each group). Group A: Albendazole (Albazole, Nawan Lab.) was given at dose rate of 5 mg/kg body weight. Group B: Levamisole (Nilverm, ICI) was given at dose rate of 7.5 mg/kg body weight. Group C: Oxfendazole (Oxafax, Glaxowellcome) was given at dose rate of 4.5 mg/kg body weight, while group D was kept as positive control non-medicated. The efficacy of anthelmintics was evaluated on the basis of reduction of eggs per gram (EPG) o f faeces on 7th, 14th and 21st day post-medication. Efficacy of Albendazole (Albazole) was 96.33%, 97.61% and 98.89% on 7th, 14th and 21st day, respectively. Efficacy of Levamisole (Nilverm) was 99.26%, 100% and 100% on 7th, 14th and 21st day, respectively. Efficacy of Oxfendazole (Oxafax) was 98.39%, 99.46% and 99.82% on 7th, 14th and 21st day, respectively. It was concluded from the above results that Levamisole (Nilverm) was more effective than Albendazole (Albazole) or Oxfendazole (Oxafax). However, Oxfendazole showed better efficacy than that of Albendazole.
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