Inducing heterophilia in the chicken intestine by Eimeria colchici
2004
Sevcikova, Z.,University of Veterinary Medicine, Kosice (Slovak Republic) | Goldova, M. | Revajova, V. | Levkutova, M. | Levkut, M.
The aim of this study was to create a concept of "preven- tive activation" of heterophils as a means of promoting the defence of poultry against pathogens by the introduction of a pheasant Eimeria colchici into Leghorn chicks as a non-specific host and to study the activation and migration of heterophils to the site of infection. In the Leghorn chicks, the total number of heterophils counted in the different sites of intestine was smaller than in the natural host. The number of counted heterophils showed, as in natural host,a gradual increase along with the develop-ment. In the Leghorn chicks, we saw only a first change schizont development. The low number of heterophils with Leghorn chicks as a part of host inflammatory response is due to an incompletely developed parasite along with minimal tissue damage. These changes can be thought as a model for the preventive activation of heterophils as a means of promoting the defence of poultry against patho-gens and finally as an "immune-potentiality" creation in immune responses to any infectious organisms.
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