Chemical specification of Gynostemma pentaphyllum (Thunb.) makino
2005
Warunee Jirawattanapong(Department of Medical Sciences, Nonthaburi (Thailand). Medicinal Plant Research Institute) | Jaree Bansiddhi(Department of Medical Sciences, Nonthaburi (Thailand). Medicinal Plant Research Institute) | Yenchit Techadamrongsin(Department of Medical Sciences, Nonthaburi (Thailand). Medicinal Plant Research Institute) | Duangpen Pattamadilok(Department of Medical Sciences, Nonthaburi (Thailand). Medicinal Plant Research Institute)
Gynostemma pentaphyllum (Thunb.) Makino (Cucurbitaceae) is of interest as a potential crude drug. Its chemical constituents were identified as gypenosides, dammarane-type saponins, which possessed various activities: antitumor, antilipemic, and anti-inflammatory activities etc. In this investigation, the quality of G. pentaphyllum collected from 13 various areas, both wild and cultivated, was examined. The chemical identifications were provided by colour reaction, froth test and TLC fingerprint. The efficient methods to determine the total saponins which are pharmaceutically valuable have been developed. Subsequently, the chemical specifications for the aerial parts of this herb were provided.
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