[Role of macrophages in immunological reactions]
2007
Malashko, V.V. | Gar'kavenko, L.V. | Malashko, D.V., Grodno State Agrarian Univ. (Belarus)
The role of macrophages in realization of immunological reactions is studied at abomazalno-enteral pathologies at calves-hypotriphics under catosal application. It is established, that the intestine plays the important role in immunological reactions of calves. Under influence of catosal the absolute quantity of macrophages increases in structures of both rennet bag and thin intestine by 27,8-56,6% in relation to the control. Considering regulating role of system of mononuclears phagocytizing at many reactions of organism, it is possible to suppose that its stimulation and oppression should influence on current and outcome of pathological process. In initial phase of inflammatory process leukocytic infiltration during this period at calves-hypotrophics is in stage of formation and it seems to be late. Conformity between lymphocytes, plasmocytes and macrophages makes 1:5,2:9.8. As a result of catosal usage this parity has made: 1:12,5:25,6. In process of increase in quantity of macrophages leukocytic and fibroblastic infiltration of rennet bag mucosa and thin intestine enhanced. Thus link between micropages quantity and intensity of immunological reactions was observerd. Experiment has shown that under influence of catosal for 2 days there was increase of macrophages content in relation to the control parameter on 27,8 % (Р 0,05). The most essential deflections in the absolute macrophages content was noted between 2th and 4th days of preparation application. Concentration of macrophages has raised on 44.2-56,6 % (P 0,05) in relation to the first day of research.
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