Copper resistance in bacteria and its regulation
2004
Irawati, W.((Universitas Gadjah Mada, Yogyakarta (Indonesia). Pusat Studi Bioteknologi)) | Yuwono, T. | Hartiko, H. | Soedarsono, J.((Universitas Gadjah Mada, Yogyakarta (Indonesia)))
The presence of high concentration of cupric ions in the environment promotes selection of microorganisms possessing genetic determinants for copper resistance. Previous research suggests that copper resistance bacteria can be selected from extreme environmental circumstances or can be manipulated genetically to recover copper from industrial wastewater. Several examples of chromosomal and plasmid copper-resistance systems in bacteria have been reported, and the mechanisms of resistance have started to be understood at the molecular level. The Cu2+ detoxification mechanisms as adopted by bacteria include energy-dependent efflux, intracellular sequestration, precipitation as CuS, and extracellular complexation. Before deploying such a potential of bacteria to devise biotechnological methods for wastewater decontamination, it is imperative to characterize the strains in terms of their metal uptake.
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