Effect of royal jelly on bisphenol A-induced proliferation of human breast cancer cells
2007
Nakaya, M.(Kyushu Univ., Fukuoka (Japan). Faculty of Agriculture) | Onda, H. | Sasaki, K. | Yukiyoshi, A. | Tachibana, H. | Yamada, K.
Royal jelly is known as a functional food containing many useful minerals. In this study, we found an antienvironmental estrogen activity of royal jelly. Bisphenol A (BPA) is an environmental estrogen that stimulates proliferation of human breast cancer MCF-7 cells. Royal jelly inhibited the growth-promoting effect of BPA on MCF-7 cells, even though it did not affect the proliferation of cells in the absence of BPA. In addition, this inhibiting effect of royal jelly was heat-stable.
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