Evaluation of the microsatellite polymorphism in intron I of the myostatin gene (MSTN) in Latvian Blue cattle breed
2008
Mazversite, J., University of Latvia, Salaspils (Latvia). Inst. of Biology | Grislis, Z., Latvia Univ. of Agriculture, Jelgava (Latvia) | Sugoka, O., University of Latvia, Salaspils (Latvia). Inst. of Biology | Sokolovska, J., University of Latvia, Salaspils (Latvia). Inst. of Biology | Sjakste, T., University of Latvia, Salaspils (Latvia). Inst. of Biology
Myostatin (MSTN), a member of the transforming growth factor-beta (TGF-beta) superfamily, is a highly conserved, potent negative regulator of skeletal muscle growth in many species from rodents to humans. Loss of MSTN activity in cattle, mice, and humans leads to a profound phenotype of muscle overgrowth associated with more numerous and larger fibres and enhanced regenerative capacity. Several MSTN gene structural variations have been reported as potentially significant in cattle phenotype performance. Here we report preliminary data on the microsatellite polymorphism of the first intron of the MSTN gene in Latvian Blue cattle breed.
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